Research Paper Volume 8, Issue 8 pp 1593—1606
Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs)
Figure 1. Bedaquiline: Structure and Activity. Bedaquiline, also known as TMC207 and R207910, is a first-in-class diaryl-quinoline compound, that mechanistically inhibits the bacterial ATP-synthase.