Research Paper Volume 8, Issue 8 pp 1703—1717
Paracrine effects of human adipose-derived mesenchymal stem cells in inflammatory stress-induced senescence features of osteoarthritic chondrocytes
Figure 5. Effect of CM on MAPK. OA chondrocytes were incubated with IL-1β and/or CM for 15 min and immunoblotting was performed for phosphorylated and total p38, ERK1/2 and JNK1/2. Data are shown as mean±standard deviation of N=3 separate experiments with cells from separate donors. ++p<0.01 with respect to non-treated cells; *p<0.05, **p<0.01 with respect to IL-1β-treated cells.