Research Paper Volume 8, Issue 9 pp 2153—2181

Age-related changes in cerebellar and hypothalamic function accompany non-microglial immune gene expression, altered synapse organization, and excitatory amino acid neurotransmission deficits


Figure 6. Microglial-specific expression of immune transcripts found upregulated with age in whole tissue (A) C57BL/6 cerebellum and (B) BALB hypothalamus. Values in each bar depict number of biological replicates. With the exception of C3 expression in the C57BL/6 cerebellum, no transcripts increase microglial expression with age. Values in the boxes above each graph show overall changes in transcript expression from whole tissue RT-qPCR experiments.