Expression of Concern
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This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 8, Issue 10 pp 2509—2524
MicroRNA-346 facilitates cell growth and metastasis, and suppresses cell apoptosis in human non-small cell lung cancer by regulation of XPC/ERK/Snail/E-cadherin pathway
Figure 1. MiR-346 is up-regulated in primary human lung cancer and NSCLC cell lines, and predicts a worse prognosis. (A) miR-346 is significantly increased in primary human lung cancer tissues in comparison to adjacent-normal lung cancer tissues. n=114 for each group. (B) The expression level of miR-346 in seven NSCLC cell lines and normal 16HBE cells. Assays were performed in triplicate. (C) Kaplan-Meier survival analysis revealed that up-regulated miR-346 is associated with poor prognosis in patients with non-small cell lung cancer. *P < 0.001, Means ± SEM was shown. Statistical analysis was conducted using student t-test.