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Research Paper Volume 8, Issue 10 pp 2509—2524

MicroRNA-346 facilitates cell growth and metastasis, and suppresses cell apoptosis in human non-small cell lung cancer by regulation of XPC/ERK/Snail/E-cadherin pathway

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Figure 2. Expression of XPC is up-regulated in primary human lung cancer and negatively expressed related to miR-346. (A-B) Western-blot of XPC protein and qRT-PCR of XPC mRNA in lung cancer tissues and adjacent-normal lung cancers. n=114 for each group. C. Scatter plots showing the inverse association between miR-346 level and XPC mRNA expression. *P < 0.001, Means ± SEM was shown. Statistical analysis was conducted using student t-test.