Figure 1. Locomotor activity of aged rats in the open field test. (A, B) Horizontal and (C) vertical locomotor activity for males (white bar), GDX males (black bar) and females (grey bar). There were no significant differences between groups in horizontal locomotor activity. Females had a significantly higher vertical locomotor activity compared to both male groups (p<0.05). Data are expressed as means + SEM. *p<0.05.