Research Paper Volume 8, Issue 11 pp 2848—2861

Figure 2. Anxiety-like behavior in aged rats. (A) Time spent in the center zone of the open field, (B) time spent in the light zone of the light/dark box and (C) time spent in the open arms of the elevated plus maze. No significant difference between the groups was found in the time spent in the center zone. GDX males were less anxious than males in light/dark box (p<0.01). There was no significant difference in the time spent in open arms between groups in elevated plus maze. Males (white bar), GDX males (black bar) and females (grey bar). Values are expressed as means + SEM. **p<0.01.