Figure 8. Plasma testosterone concentration. (A) Plasma testosterone concentration 4 weeks following gonadectomy. Gonadectomy led to a significantly lower testosterone concentration compared to control males (p<0.01). Males (white bar) and GDX males (black bar). (B) Plasma testosterone concentration in young and aged male rats. Aged males (30 months) had significantly lower plasma testosterone concentration compared to young males (p<0.001) [young males (white bar), aged males (black bar)]. Values are expressed as means + SEM. **p<0.01, ***p<0.001.