Research Paper Volume 8, Issue 11 pp 2848—2861

Figure 9. Immobility duration in forced swim test after acute testosterone treatment. (A) Plasma testosterone concentration 30 minutes after acute treatment with olive oil vehicle (VEH) or testosterone propionate (TP) in aged GDX males and aged females. Acute testosterone treatment caused an increase in plasma testosterone concentration in both GDX males and females compared to their vehicle treated controls (p<0.01). (B) Immobility time in the forced swim test during the 3 min testing period, (C) immobility duration in the 1^st min, (D) 2^nd min, (E) 3^rd min and (F) the latency to first immobility without any significant differences in observed behavioral parameters between groups. Values are expressed as means + SEM. *p<0.05, **p<0.01. Females+VEH (grey bar), Females+TP (grey striped bar), GDX+VEH males (black bar), GDX+TP males (black striped bar).