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Research Paper Volume 8, Issue 11 pp 3131—3146

Early age decline in DNA repair capacity in the liver: in depth profile of differential gene expression

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Figure 4. ClueGo network analysis of differentially expressed genes reveal sustained activation of p53-related pathways. Annotation module network generated as in Fig. 4 for differentially expressed genes 6 days after DEN (A) and for the 67 common transcripts for 2 and 6 days after DEN in 6-month-old mice (B), demonstrating that in contrast to 1-month-old mice p53-related pathways did not resolve in 6-month-old mice. The node size represents the term enrichment significance.