Research Paper Volume 10, Issue 1 pp 83—99

Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury


Figure 6. Effects of resveratrol on the expression of SIRT1-related proteins. Representative western blots of SIRT1, phospho-Thr172 AMPK, PPARα, PGC-1α, and ERR-1α protein levels (A). Compared with the control (Cont) group, expression of SIRT1 was significantly increased in the RSV group (B). The phospho-Thr172 AMPK/total AMPK ratio was also increased in the RSV group (C). PPARα, PGC-1α and ERR-1α protein levels were higher in RSV than in Cont (D-F). Quantitative analysis of the results is shown (*P<0.05, †P<0.01).