Figure 4. Unique age-related transcriptomic response to concentric and eccentric exercise. Overlap of age-associated differentially expressed genes within contraction modes. Both young and older muscle display unique signatures of differential gene expression 5 h post-concentric (up-regulated, top left Venn; down-regulated, top right Venn) and post-eccentric (up-regulated, bottom left Venn; down-regulated, bottom right Venn) exercise.