Research Paper Volume 12, Issue 6 pp 4711—4726

Silencing of lncRNA XIST inhibits non-small cell lung cancer growth and promotes chemosensitivity to cisplatin

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Figure 6. Induction of pyroptosis by DDP in NSCLC cells and facilitatory role of XIST. (A) Analysis of apoptosis by annexin V/PI staining and flow cytometry in NSCLC cells. (B) Western blot detection of apoptosis-related proteins. (C) Morphological changes in si-XIST-transfected, DDP-treated NSCLC cells. (D, E) Western blot analysis of pyroptosis-related proteins. * < 0.05 vs si-nc group, # < 0.05 vs DDP + si-nc group.