Figure 4. Ubiquinol-10 rescued aging-induced reduction of mitochondrial biogenesis. Protein levels of SIRT1 (A and B) and PGC-1α (C and D) in aging 0 h, 24 h, and 48 h oocytes. Protein levels of SIRT1 (E and F) and PGC-1α (G and H) in Ctrl-24 h and Ubi-24 h oocytes. (I) mtDNA copy number in 0 h, Ctrl-24 h, Ubi-24 h, Ctrl-48 h, and Ubi-48 h oocytes. ns, p > 0.05, *p < 0.05, and ***p < 0.001 indicate significant differences.