Figure 2. The cross-sectional associations of BMI categories with brain volumes in the whole population. Higher BMI categories were associated with larger volumes of hippocampus (A), entorhinal cortex (B) and middle temporal lobe (C). All analyses were adjusted for adjusting for age, sex, education, cognitive diagnosis, ApoE ε4 status, prevalent comorbidities (i.e., hypertension, hyperlipemia, DM2, depression and CVD) and total intracranial volumes. Abbreviations: BMI = body mass index;CVD = Cardiovascular Diseases;DM2 = Diabetes Mellitus Type 2.