Figure 1. Relationship between mRNA expression patterns of PDIs in gliomas with different clinical characteristics (cancer type, WHO grade, the status of IDH and 1p19q). The heat maps, based on the public data from TCGA and CGGA databases, demonstrated upregulated mRNA (red) or downregulated mRNA (blue) of the PDI family members in the subgroups. TCGA database as training set and CGGA database as the validation set. * p < 0·05, ** p < 0·01, *** p <0·001.