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Research Paper Volume 12, Issue 3 pp 3025—3041
Obg-like ATPase 1 (OLA1) overexpression predicts poor prognosis and promotes tumor progression by regulating P21/CDK2 in hepatocellular carcinoma
Figure 5. Depletion of OLA1 promotes apoptosis in HCC cells. (A–D) Flow cytometry was performed to determine the level of cell apoptosis in si-OLA1 groups. (E–G) Western blot analysis showed that knockdown of OLA1 upregulated P21, BAD and cleaved caspase 3 levels and downregulated Bcl-2 levels in HCC cells. All *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001.