Figure 7. MCM3 and SPATS2 promotes HCC cell proliferation. (A–B) Proliferation of HCC cells with MCM3 or SPATS2 knockdown according to CCK-8 analysis. (C–D) EdU assays showing the proportion of S-phase cell after downregulating the expression of MCM3 or SPATS2. Nuclei of S-phase cells were pink. (E–H) Statistical analysis of EdU incorporation. *P < 0.05; **P < 0.01; ***P < 0.001.