Research Paper Volume 12, Issue 9 pp 7694—7703

Genetic variant of COL11A2 gene is functionally associated with developmental dysplasia of the hip in Chinese Han population

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Figure 2. Relationship between the genotype of rs9277935 and COL11A2 expression in DDH joint tissues. (A) DDH Patients with genotype TT have a significantly increased expression of COL11A2 than those with GG (p = 0.02 for articular cartilage; p = 0.036 for joint ligament). (B) Immunofluorescent assay of COL11A2 (green) expression and nucleus (blue) in the cartilage and ligament tissues in DDH patients with different genotypes observed under confocal microscopy.