Research Paper Volume 12, Issue 9 pp 7774—7785

Figure 3. Downregulation of hsa_circ_0018818 inhibits NSCLC cells proliferation. (A) The overlap of these differentially expressed circRNAs was analyzed. (B) RT-qPCR analysis of hsa_circ_0018818 gene expression in NSCLC and adjacent normal tissues. (C) RT-qPCR analysis of hsa_circ_0018818 gene expression in BEAS-2B, A549, PC-9, NCI-H1441 and NCI-H1650 cells. (D, E) Suppression of hsa_circ_0018818 expression after transfection of A549 and NCI-H1650 cells with shRNA for 24 h. (F, G) CCK-8 assays of A549 and NCI-H1650 cell proliferation. Shown are the OD₄₅₀ values. **P< 0.01 vs. control.