Research Paper Volume 12, Issue 9 pp 8728—8741
High PRMT5 expression is associated with poor overall survival and tumor progression in bladder cancer
Figure 5. PRMT5 had a strong oncogenic function in bladder cancer. (A) Western blotting showed that PRMT5 was efficiently knocked down by PRMT5-shRNA. (B) Representative images of the tumor xenografts inoculated with T24-shC and T24-sh1 cells and hematoxylin and eosin staining of tumor xenografts are shown. (C–E) Growth curve and histogram analysis of the size and weight of xenograft tumors. Error bars show the standard error of the mean. sh, short hairpin RNA; T24-shC: T24-shRNA/negative control; T24-sh1: T24-shRNA. *P < 0.05, **P < 0.01.