Research Paper Volume 12, Issue 19 pp 18982—19011
POC1A acts as a promising prognostic biomarker associated with high tumor immune cell infiltration in gastric cancer
POC1A was a significant anti-tumor gene in gastric cancer. (A–F) Comparison of mRNA expression of 6 significant genes (LAMP5, CEBPB, ARMC9, POC1A, PAOX, VMP1) from LASSO regression analysis in tumor and adjacent tissues (n=101). (G–I). Ratio the mRNA expression of 6 genes comparing 2(-CT) in tumor tissues with 2(-CT) in matched normal tissues (n=101). (M) mRNA expression of POC1A in tumor (n=111) tissues was significantly higher than normal (n=21) tissues from GSE54129. (N) Intensity of immunohistochemistry staining of POC1A in normal tissue was higher than intensity in tumor tissue from the same patient.