Research Paper Volume 12, Issue 19 pp 19012—19021
Apremilast ameliorates ox-LDL-induced endothelial dysfunction mediated by KLF6
Apremilast ameliorated ox-LDL-induced reduction of KLF6 in human umbilical vein endothelial cells (HUVECs). Cells were treated with ox-LDL (100 μg/mL) in the presence or absence of apremilast (0.5, 1 μM) for 24 h. (A) mRNA of KLF6; (B) Protein of KLF6 (*, #, $, P<0.01 vs. previous column group, n=4-5).