Priority Research Paper Volume 12, Issue 19 pp 18804—18821
The slc4a2b gene is required for hair cell development in zebrafish
slc4a2b knockdown leads to decreased HC clusters in the posterior lateral line of zebrafish. (A–D) Zebrafish injected with slc4a2b-morpholino (MO) had normal morphology (B’’, D’’, F’’, H’’) but decreased HC clusters in the posterior lateral line (B’, D’, F’, H’) compared to the controls (Ctrl) (A’’, C’’, E’’, G’’ and A’, C’, E’, G’) at different developmental stages. The HC clusters in the posterior lateral line are indicated by yellow arrows. (I) Quantification of the number of HC clusters in the posterior lateral line in slc4a2b-morphants and controls at different developmental stages. ***P < 0.001.