Figure 2. Construction of DEG signature. Volcano plot for displaying differentially expressed genes in GSE26712 cohort (A), the procedure of data dimension reduction by lasso algorithm to select the optimal candidate genes (B), and the optimal cutoff of DEG signature calculated by the maximally selected rank statistics (C), the Kaplan-Meier curve grouped by DEG signature in training cohort (D) and external validation cohort (F), and the risk score analysis in the training cohort (E).