Serum and exosomal LDHC expressions were correlated with clinicopathological characteristics in HCC. Correlations between serum LDHC expressions and clinical indices encompassing (A) AFP, (B) PIVKA-II, (C) GP-73, (D) CEA, and (E) CA19-9 were analyzed. Serum exosomal LDHC expressions were associated with (F) AFP, and (G) PIVKA-II, but not correlated with the levels of (H) GP-73, (I) CEA, and (J) CA19-9 in patients with HCC.