A significant elevation in the ABR threshold was induced by noise exposure in the NIHL group. (A) ABR frequency-threshold curves for the NIHL and control groups. (B) ABR frequency-averaged thresholds for the NIHL and control groups. The values are presented as the mean ± SE of 32 mice per group. *** P<0.001 in post hoc comparisons between the NIHL group and the control group using two-way repeated measures ANOVA (A) or t-test (B).