Research Paper Volume 12, Issue 19 pp 19597—19617
Characterization of the expression and prognostic value of 14-3-3 isoforms in breast cancer
Expression and oncogenic role of 14-3-3 zeta in BrCa. (A) Representative microphotographs revealing 14-3-3 zeta expression in BrCa and normal tissues using IHC staining. (B) T-test analysis of 14-3-3 zeta expression in BrCa and normal tissues. (C) 14-3-3 zeta protein downregulation after transfection of 14-3-3 zeta-specific siRNA. The 14-3-3 zeta-specific siRNA suppressed the (D) viability, (E) migration, and (F) invasion of MDA-MB-231 cells.