Generalized correlation coefficient for genome-wide association analysis of cognitive ability in twins

Afsaneh Mohammadnejad; Marianne Nygaard; Shuxia Li; Dongfeng Zhang; Chunsheng Xu; Weilong Li; Jesper Lund; Lene Christiansen; Jan Baumbach; Kaare Christensen; Jacob v. B. Hjelmborg; Qihua Tan

doi:doi:10.18632/aging.104198

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Research Paper Volume 12, Issue 22 pp 22457—22494

Generalized correlation coefficient for genome-wide association analysis of cognitive ability in twins

Figure 3. QQ plot comparing the performance of GCC, kinship and LME models in Danish (A) and Chinese (B) GWAS data. The left QQ plot is from Danish sample and the right QQ plot is from Chinese sample. In each plot, x-axis is the expected p-value and y-axis is the observed p-value from the GWAS.