Research Paper Volume 13, Issue 5 pp 7067—7083

Figure 6. GIT1 deficiency inhibits BMECs proliferation and angiogenesis in vitro. (A) ELISA detection of VEGF in the CM of BMECs from the different groups after being treated with or without myelin debris for 72 h. (B, D) Proliferation of BMECs cultured with CM from the different groups examined by CCK8 at 0, 1, 2, and 3 d. (C, E) Migration and tube formation of BMECs treated with CM from the different groups. The images of scratch wound and tube formation assays (left) and quantification of the migration ability and cumulative tube length (right). Scar bar, 100 μm. N = 6 in each group. NS represents no significance, ^*p < 0.05, ^**p < 0.01, ^***p < 0.001.