Research Paper Volume 13, Issue 5 pp 7067—7083

Figure 7. GTI1 promotes MECs to clear myelin debris via autophagy pathway. (A) BMECs from the GIT1 WT and KO mice were transfected with the mRFP-GFP-LC3 adenovirus. The cells nuclei were stained using DAPI (blue). Bar, 10 μm. (B) Numbers of yellow and red puncta. (C–F) LC3, P62, and VEGF levels in BMECs from the GIT1 WT and KO mice after being treated with or without myelin debris for 72 h. N = 6 in each group. NS indicates no significance, ^*p < 0.05, ^**p < 0.01, ^***p < 0.001.