Research Paper Volume 13, Issue 5 pp 7589—7607

Figure 7. Fecal microbiota transplantation enhances proliferation of vaginal cells. (A). Representative images of PCNA and ESR1 immunohistochemical staining in vaginas from OVX+FMT, OVX+NST, Sham+FMT and Sham+ NST groups, (magnification 200x). (B). Positive rate of PCNA in vaginal epithelial cells in the OVX+FMT (n=11), OVX+NST (n=11), Sham+FMT (n=10) and Sham+NST (n=9) groups (one-way ANOVA, F_{3, 37}=234.68, P<0.01). (C) Positive rate of ESR1 in vaginal epithelial cells in the OVX+FMT (n=11), OVX+NST (n=11), Sham+FMT (n=10) and Sham+NST (n=9) groups (one-way ANOVA, F_{3, 37}=243.5, P<0.01). (D) Serum E1 and E2 level of the OVX+NST group (n=6) and the OVX+FT (n=6) group mice (t-test, P>0.05). Data are shown as mean ± SEM. *P < 0.05, **P < 0.01. PCNA: proliferating cell nuclear antigen; ESR1: estrogen receptor alpha; E1: Estrone; E2: Estradiol.