Research Paper Volume 13, Issue 6 pp 8078—8094
Flotillin-2 promotes cell proliferation via activating the c-Myc/BCAT1 axis by suppressing miR-33b-5p in nasopharyngeal carcinoma
Figure 1. FLOT2 positively regulates and predicts poor prognosis in NPC. (A, B) qPCR and western blot assays indicating the level of BCAT1 mRNA and protein in 5-8F-shFLOT2, 6-10B-BCAT1 and control cells. (C) The representative IHC pictures indicating the co-expression patterns of FLOT2 and BCAT1 in patients with NPC (magnification, 200×). (D) Spearman correlation analysis indicating the positive correlation between FLOT2 and BCAT1 in NPC. (E) Kaplan-Meier survival analysis showing the level of FLOT2 and BCAT1 negatively associates with overall survival outcome in NPC.