Figure 2. The regulatory network of TF and univariate cox analysis of differentially expressed IRGs and OS of HNSCC. (A) The regulatory network constructed based on prognosis-related IRGs and TFs. The red circle represents the high-risk IRGs and the green circular represents the low-risk IRGs. The triangle represents differentially expressed TFs. The red link line represents positive regulation, while there was no observed negative regulation. (B) A total of 24 differentially expressed IRGs found to be significantly associated with the OS of HNSCC patients (p-value < 0.01). Red points represent positive correlations, while green points represent negative correlations.