Characterizing a long-term chronic heart failure model by transcriptomic alterations and monitoring of cardiac remodeling

Yingqi Zhu; Qiancheng Wang; Hairuo Lin; Kaitong Chen; Cankun Zheng; Lin Chen; Siyuan Ma; Wangjun Liao; Jianping Bin; Yulin Liao

doi:doi:10.18632/aging.202879

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Research Paper Volume 13, Issue 10 pp 13585—13614

Characterizing a long-term chronic heart failure model by transcriptomic alterations and monitoring of cardiac remodeling

Figure 3. Pathways most affected at 1 month and 8 months after MI. (A) PCA analysis show that the transcriptome of mice after LCA ligation changes significantly and varies with time. (B) Overlap of significantly modulated genes between 1 month and 8 months post-MI. (C) GGO (left) and EGO (right) analysis of pathways affected by long term MI.