Characterizing a long-term chronic heart failure model by transcriptomic alterations and monitoring of cardiac remodeling

Yingqi Zhu; Qiancheng Wang; Hairuo Lin; Kaitong Chen; Cankun Zheng; Lin Chen; Siyuan Ma; Wangjun Liao; Jianping Bin; Yulin Liao

doi:doi:10.18632/aging.202879

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Research Paper Volume 13, Issue 10 pp 13585—13614

Characterizing a long-term chronic heart failure model by transcriptomic alterations and monitoring of cardiac remodeling

Figure 4. Serial echocardiographic assessment of post-infarction remodeling. (A) Representative recordings of M-mode echocardiographic images at indicated time points. (B) Left ventricular end-systolic diameter (LVESd). (C) Left ventricular end-diastolic diameter (LVEDd). (D) Left ventricular systolic function presented by the left ventricular ejection fraction (LVEF). (E) Left ventricle fractional shortening (LVFS). ^*P < 0.05 vs the corresponding time point in the sham group. ^#P < 0.05 compared with the prior time point in the MI group. n = 8–10 at various time points.