Research Paper Volume 13, Issue 7 pp 9373—9397

Differential role of melatonin in healthy brain aging: a systematic review and meta-analysis of the SAMP8 model


Figure 3. Risk of bias. (A) Overall RoB for each item in the SYRCLE tool for all included studies. Each RoB item is presented as a percentage based on all included studies. (B) Individual RoB for each of the included animal studies. Each item in the SYRCLE tool was scored as ‘yes’, ‘no’, or ‘unclear’.