Research Paper Volume 13, Issue 9 pp 12565—12586
Investigation and verification of the clinical significance and perspective of natural killer group 2 member D ligands in colon adenocarcinoma
Figure 5. Immunohistochemical staining analyses of ULBP2 expression in COAD tumor tissues and adjacent normal tissues. (A–D) ULBP2 staining results were observed in the cytoplasm of colon cells; (A) Positive staining of COAD tumor tissues; (B) Negative staining of COAD tumor tissues; (C) Positive staining of adjacent normal colon tissues; (D) Negative staining of adjacent normal tissues; (E, F) Diagnostic analysis of ULBP2 expression in COAD: (E) Scatter plot; (F) Diagnostic ROC curve; survival analysis of ULBP2 expression in COAD: (G, H) Kaplan–Meier survival curve of ULBP2 protein expression in COAD OS and RFS; (I, J) Stratified analysis of ULBP2 expression in different clinical parameter layers in COAD patients: (A) OS; (B) RFS. Notes: COAD, colon adenocarcinoma; ULBP: unique long 16 (UL16)-binding protein; ROC, receiver operating characteristic; AUC: area under the curve; CI: confidence interval; OS, overall survival; RFS, recurrence-free survival. Magnification, 200×.