Figure 2. The disease burden of CAVD in 21 GBD regions from 1990 to 2019. (A) Incident cases; (B) ASIR; (C) prevalent cases; (D) ASPR; (E) deaths; (F) ASDR. Abbreviations: CAVD, calcific aortic valve disease; GBD, global burden of disease; ASIR, age-standardized incidence rate; ASPR, age-standardized prevalence rate; ASDR, age-standardized deaths rate.