Identification of key pathways and genes in carotid atherosclerosis through bioinformatics analysis of RNA-seq data

Zhongchen Li; Jiheng Hao; Kun Chen; Qunlong Jiang; Peijian Wang; Xiaohui Xing; Jiyue Wang; Yinjiang Zhang; Yilei Xiao; Liyong Zhang

doi:doi:10.18632/aging.202943

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Research Paper Volume 13, Issue 9 pp 12733—12747

Identification of key pathways and genes in carotid atherosclerosis through bioinformatics analysis of RNA-seq data

Figure 3. GO and KEGG enrichment analysis of DEGs. (A) GO enrichment analysis of DEGs, BP represents the biological process, CC represents the cellular component, and MF represents the molecular function. (B) KEGG pathway analysis of DEGs, adj.p.Val is corrected p-value, the count represents the number of DEGs. (C) Interaction between DEGs and top 5 terms of GO entries. (D) Interaction between DEGs and top 5 disease pathways in KEGG. DEGs: Differentially expressed genes. KEGG: Kyoto Encyclopedia of Genes and Genomes. FC: Fold change. Adj.p.Val: corrected p-value.