Research Paper Volume 13, Issue 9 pp 12919—12928

Knockdown of ZFAS1 improved the cardiac function of myocardial infarction rats via regulating Wnt/β-catenin signaling pathway

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Figure 3. Promotion of Wnt/β-catenin pathway by shZFAS1 in the MI rats. (A) The protein expression of β-catenin and GSK-3β in the myocardial tissues was measured. (B) Influence of shZFAS1 on the protein expression of β-catenin and GSK-3β in the myocardial tissues. (C) Influence of shZFAS1 on the mRNA levels of β-catenin and GSK-3β in the myocardial tissues. (D) The expression of β-catenin and GSK-3β in the myocardial tissues were measured using IHC staining (Scale bar = 500 μm). (E) Influence of shZFAS1 on β-catenin and GSK-3β in the myocardial tissues. *P < 0.05 compared with the group sham. #P < 0.05 compared with the group MI.