Research Paper Volume 13, Issue 9 pp 12919—12928

Figure 5. Inhibition of Wnt/β-catenin pathway remarkably reversed the influence of shZFAS1 on CFs viability. (A) Cell migration was measured using wound healing method (Scale bar = 500 μm). (B) XAV939 markedly suppressed the ability of cell migration compared with group hypoxia+shZFAS1. (C) Cell invasion was measured using Transwell method (Scale bar = 200 μm). (D) XAV939 markedly suppressed the ability of cell invasion compared with group hypoxia+shZFAS1. (E) XAV939 markedly suppressed the ability of cell proliferation compared with group hypoxia+shZFAS1. ^*P < 0.05 compared with the group sham. ^#P < 0.05 compared with the group hypoxia. ⁺P < 0.05 compared with the group hypoxia+shZFAS1.