Research Paper Volume 13, Issue 10 pp 14109—14130

Rheumatoid arthritis and osteoporosis: a bi-directional Mendelian randomization study

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Figure 1. Workflow of bi-directional MR analysis. (A) The fundamental idea of MR analysis: If we cannot randomize the exposure, we can find a randomized instrumental variable to disentangle (B) Workflow of our bi-directional MR analysis. MR: Mendelian randomization; BMD: Bone mineral density; RA: Rheumatoid arthritis.