Figure 1. Differentially expressed pathways and potential transcriptional regulators of lungs from old and young mice. (A) Top 10 ranked high- and down Z-score pathways. (B) Upstream regulators. (C) Transcription regulators. Orange bars represent overexpressed genes; blue bars represent underexpressed genes, all of them at a significant level of p< 0.05. These results were obtained using Ingenuity Pathway Analysis™.