Research Paper Volume 13, Issue 10 pp 14342—14354
LncRNA MEG8 promotes TNF-α expression by sponging miR-454-3p in bone-invasive pituitary adenomas
Figure 6. Mechanism and function of TNF-α in BIPAs progress. LncRNA MEG8 promotes TNF-α expression by sponging miR-454-3p, and then TNF-α directly induce osteoclast differentiation in BIPAs, which further leads to bone destruction.