Figure 2. Forest plot reflecting the association between SII and OS in pancreatic cancer. A random-effects model (REM) was used because of significant heterogeneity (I2 = 76.4%, P < 0.001). The pooled HR and 95%CI are: HR=1.50, 95%CI=1.15-1.96, p=0.002. SII= systemic immune-inflammation index, OS=overall survival.