Research Paper Volume 13, Issue 16 pp 20836—20852

Heparanase is a novel biomarker for immune infiltration and prognosis in breast cancer

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Figure 3. Correlation of HPSE expression with immune infiltration level in BLCA and BRCA. In BLCA, HPSE expression has no correlation with infiltrating levels of B cells, medium correlation with infiltrating levels of CD8+ T cells, weak correlation with infiltrating levels of CD4+ T cells and macrophages, and a strong correlation with infiltrating levels of neutrophils and dendritic cells. In BRCA, HPSE expression has medium correlation with infiltrating levels of B cells, CD8+ T cells, CD4+ T cells, and macrophages, and a strong correlation with infiltrating levels of neutrophils and dendritic cells.