Research Paper Volume 13, Issue 23 pp 25138—25152

Figure 3. Overexpressing SNHG3 enhances gastric cancer cell growth and metastasis. (A) SNHG3 expression in BGC-823 and AGS cells was assessed following pcDNA3.1-SNHG3 transfection. *P<0.01 vs. the pcDNA3.1-NC group. (B) Transfected cell proliferation was assessed via CCK-8 assay. *P<0.01 vs. the pcDNA3.1-NC group. (C) Cell cycle progression in BGC-823 and AGS cells transfected with pcDNA3.1-SNHG3 was assessed via flow cytometry. (D, E) BGC-823 and AGS cell colony forming activity was assessed following SNHG3 overexpression. *P<0.01 vs. the pcDNA3.1-NC group. (F–I) Transwell migration and invasion assays were used to assess BGC-823 and AGS cells following pcDNA3.1-SNHG3 transfection. *P<0.01 vs. the pcDNA3.1-NC group.