Research Paper Volume 14, Issue 6 pp 2590—2606

Figure 8. Expression of hippocampal proteins of POD model in aged mice. Six hour postoperatively (A, B) Compared with the C group, TLR4, p-NF-κB p65, IκBα, p-IκBα, IL-6, IL-1β, and MAGI-2 expression was elevated in the AS group. MAGI-2 expression was higher in the ASP group than in the C group. p-NF-κB p65, IκBα, IL-6, IL-1β and MAGI-2 expression was lower in the ASP group than in the AS group. Compared with the C group, ^*p<0.05, ^**p<0.01, ^***p<0.001; compared with the AS group, ^#p<0.05, ^##p<0.01. Nine hour postoperatively (C, D) Compared with the C group, the expression of TLR4, p-NF-κB p65, p-IκBα, IL-6, IL-1β, and MAGI-2 was elevated in the AS group, and the expression of TLR4, IL-1β and MAGI-2 in the ASP group was higher than that in the C group; compared with the AS group, the expression of TLR4 in the ASP group was decreased (Figure 8). Compared with the C group, ^*p<0.05, ^**p<0.01, ^***p<0.001; compared with the AS group, ^#p<0.05, ^##p<0.01. Twenty-four hour postoperatively (E, F) Compared with the C group, p-NF-κB p65 expression was elevated in the AS group, and the p-NF-κB p65 expression was lower in the ASP group than in the AS group. Compared with the C group, ^*p<0.05, ^**p<0.01, ^***p<0.001; compared with the AS group, ^#p<0.05, ^##p<0.01.