Adipose-derived mesenchymal stem cells may reduce intestinal epithelial damage in ulcerative colitis by communicating with macrophages and blocking inflammatory pathways: an analysis <i>in silico</i>

Nan Zhang; Yixuan Chen; Chengyu Huang; Mengxin Wei; Ting Li; Yufeng Lv; Qiong Song; Shaowen Mo

doi:doi:10.18632/aging.203964

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Research Paper Volume 14, Issue 6 pp 2665—2677

Adipose-derived mesenchymal stem cells may reduce intestinal epithelial damage in ulcerative colitis by communicating with macrophages and blocking inflammatory pathways: an analysis in silico

Figure 2. Immune cell landscape in UC. (A) Manhattan plot. The DEGs in 51 cell types between UC patients and healthy individuals. (B) Enrichment of DEGs in functional pathways of the Kyoto Encyclopedia of Genes and Genomes. (C) Sankey plot, showing communication among immune cells of different types via ligand-receptor pairs. DEGs: Differentially expressed genes. UC: ulcerative colitis.